Patterns of olivocochlear axonal branches.
نویسندگان
چکیده
The olivocochlear (OC) pathway is the source of major feedback control of ascending acoustic information. Two main patterns of axonal branching are evident at this and other levels of the auditory pathway: long-distance collaterals and branches involved in feedback-control loops. Only a minority of OC neurons project to both cochlea, consistent with a role for the system in sound localization. OC branches to the ventral cochlear nucleus provide the anatomical substrate for a feedback control loop that could aid in modulating the intensity of acoustic information being conveyed to higher cortical levels while still dampening the overall intensity of signaling from the cochlea itself.
منابع مشابه
Cell Type-Specific Structural Plasticity of Axonal Branches and Boutons in the Adult Neocortex
We imaged axons in layer (L) 1 of the mouse barrel cortex in vivo. Axons from thalamus and L2/3/5, or L6 pyramidal cells were identified based on their distinct morphologies. Their branching patterns and sizes were stable over times of months. However, axonal branches and boutons displayed cell type-specific rearrangements. Structural plasticity in thalamocortical afferents was mostly due to el...
متن کاملDevelopment of layer-specific axonal arborizations in mouse primary somatosensory cortex.
In the developing neocortex, pyramidal neurons use molecular cues to form axonal arbors selectively in the correct layers. Despite the utility of mice for molecular and genetic studies, little work has been done on the development of layer-specific axonal arborizations of pyramidal neurons in mice. We intracellularly labeled and reconstructed the axons of layer 2/3 and layer 5 pyramidal neurons...
متن کاملAxonal branching in lateral olfactory tract is promoted by Nogo signaling
Mitral cells are major projection neurons of the olfactory bulb (OB) that form an axonal bundle known as the lateral olfactory tract (LOT). After axonal bundle formation, collateral branches sprout from primary axons of the LOT. Recently, we identified LOT usher substance (LOTUS) as an endogenous Nogo receptor-1 (NgR1) antagonist and demonstrated that LOTUS contributes to the formation of the L...
متن کاملBrainstem branches from olivocochlear axons in cats and rodents.
Horseradish peroxidase was used to label axons of olivocochlear (OC) neurons by intracellular injections in cats and extracellular injections in rodents. These axons arise from cell bodies in the superior olivary complex and project to the cochlea. En route to the cochlea, the thick axons (greater than 0.7 micron diam.) of medial olivocochlear (MOC) neurons formed collaterals that terminated in...
متن کاملReorganization of exuberant axonal arbors contributes to the development of laminar specificity in ferret visual cortex.
Layer-specific cortical axons are believed to develop precisely from the outset without making exuberant branches in incorrect cortical layers. We tested this hypothesis by following the development of axonal arbors of layer 2/3 pyramidal neurons in ferret visual cortex, which in the adult have dense axonal arbors in layers 2/3 and 5 and not in layer 4. We began our studies at earlier ages and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Open journal of neuroscience
دوره 1 شماره
صفحات -
تاریخ انتشار 2011